| 三硝基甲苯作业工人和中毒病例的血浆游离氨基酸谱分析 |
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| 引用本文： | 施荣山 常虹. 三硝基甲苯作业工人和中毒病例的血浆游离氨基酸谱分析[J]. 中华劳动卫生职业病杂志, 1990, 8(4): 200-202 |
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| 作者姓名： | 施荣山 常虹 |
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| 作者单位： | 安徽省职业病防治研究所(施荣山，冯学庆，常虹，王安莲，朱剑华，王秋萍，叶林，杨文华)，安徽省农科院中心实验室(李布青)，安徽省农科院中心实验室(胡海明) |
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| 摘 要： | 本文对从事TNT 炸药生产5年以上的工人28名,TNT 慢性中毒病例11名,进行了血浆游离氨基酸谱分析,并与25名正常健康者和20名慢性病毒性肝炎患者作了对比。结果表明TNT 作业工人和中毒病例,与慢性病毒性肝炎患者相比,胱氰酸和酪氨酸含量分別有显著和非常显著差别,支链按基酸和芳香族氨基酸的比值有非常显著的差别,支/芳比值和胱氨酸含量可作为TNT 中毒性肝病和慢性病毒性肝炎鉴别诊断的指标。
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| 关 键 词： | 三硝基甲苯 血浆游离氨基酸 中毒性肝病 览别诊断 |
Analysis Free Amino Acid Spectrum in Ssrum among Workers Exposed to Trinitrotoluene and those with Chronic Poisoning |
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| Shi Rong-shan. Analysis Free Amino Acid Spectrum in Ssrum among Workers Exposed to Trinitrotoluene and those with Chronic Poisoning[J]. Chinese journal of industrial hygiene and occupational diseases, 1990, 8(4): 200-202 |
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| Authors: | Shi Rong-shan |
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| Affiliation: | Shi Rong-shan |
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| Abstract: | Serum free amino acid spectrum in 28 workers exposed to trinitrotoluene(TNT)for more than 5 years and 11 chronic TNT poisoning were comparedwith 25 healthy adults and 20 patients with chronic viral hepatitis.Results of the Study showed that concentrations of cystine and tyrosineand the ratio of branched chain amino acid/ aromatic amino acid differssignificantly as compared with that of patients with chronic hepatitis,It is suggested that the ratio of branched chain amino acid/ aromatic aminoacid and the concentration of cystine can be used as differential diagnosisindexes between chronic TNT poisoned diseases and chronic virel hepatitis. |
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| Keywords: | Trinitrotoluene Serum free amino acid Poisoning liver diseases Differential diagnosis |
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