| 基于中药模拟炮制的乌头属植物水解机制及液质联用测定方法的研究进展 |
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| 引用本文： | 姜婷,张江,木卡代斯&#;斯依提,赵翡翠.基于中药模拟炮制的乌头属植物水解机制及液质联用测定方法的研究进展[J].中草药,2016,47(19):3543-3550. |
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| 作者姓名： | 姜婷 张江 木卡代斯&#;斯依提 赵翡翠 |
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| 作者单位： | 新疆医科大学中医学院, 新疆 乌鲁木齐 830000;新疆医科大学中医学院, 新疆 乌鲁木齐 830000;新疆医科大学中医学院, 新疆 乌鲁木齐 830000;新疆医科大学附属中医医院 药学部, 新疆 乌鲁木齐 830000 |
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| 基金项目： | 国家自然科学基金资助项目“基于中药模拟炮制和细胞膜色谱法的新疆准噶尔乌头生物碱水解机制及产物毒效活性研究”（81460603） |
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| 摘 要： | 生物碱是大多数乌头属药用植物的主要有效成分,具有较高的药理活性和药用价值,但也是其主要的毒性成分,为便于对乌头属植物水解产物的深入研究,主要从中药模拟炮制现状、乌头属植物所含的生物碱种类、水解机制研究现状及液质联用方法几个方面进行综述。
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| 关 键 词： | 乌头属 模拟炮制 生物碱 水解机制 液质联用 |
| 收稿时间： | 2016/3/15 0:00:00 |
Research progress in hydrolysis mechanism and LC-MS determination method of genus Aconitum L. based on traditional Chinese medicine simulation processing |
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| JIANG Ting,ZHANG Jiang,Mukadaisi&#;Siyiti and ZHAO Fei-cui.Research progress in hydrolysis mechanism and LC-MS determination method of genus Aconitum L. based on traditional Chinese medicine simulation processing[J].Chinese Traditional and Herbal Drugs,2016,47(19):3543-3550. |
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| Authors: | JIANG Ting ZHANG Jiang Mukadaisi&#;Siyiti and ZHAO Fei-cui |
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| Institution: | Xinjiang Medical University College of traditional Chinese Medicine, Urumqi 830000, China;Xinjiang Medical University College of traditional Chinese Medicine, Urumqi 830000, China;Xinjiang Medical University College of traditional Chinese Medicine, Urumqi 830000, China;Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical University, Urumqi 830000, China |
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| Abstract: | Alkaloids are the main active ingredients of most plants in Aconitum L., with high pharmacological activity and medicinal value. But it is also the main toxic components. As for the in-depth study on hydrolysate of plants in Aconitum L., this paper mainly summarized the current situation of Chinese medicine simulation processing, Aconitum alkaloids containing plant species, hydrolysis mechanism, and research status by LC-MS method. |
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| Keywords: | Aconitum L simulation processing alkaloids hydrolysis mechanism LC-MS |
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