梅毒性眼病患者C-反应蛋白和血沉与白细胞联合检测的价值

目的：探讨以眼病为主要表现的梅毒患者 C-反应蛋白( C-reactive protein, CRP )、血沉( erythrocyte sedimentation rate,ESR)和白细胞(white blood cell,WBC)联合检测的价值。方法：对2012-01/2015-12本院以眼部症状首诊的51例梅毒患者和50例正常对照者的快速血浆反应素环状卡片试验( RPR )及梅毒螺旋体血清凝集试验( TPPA )、CRP、ESR及WBC检测结果进行回顾性分析。
　　结果：梅毒性眼病患者CRP、WBC及ESR的阳性率分别为16%、18%和39%,明显高于正常对照组；ESR 阳性率分别与CRP、WBC 相比较,差异有统计学意义( P<0.05)；CRP、WBC及ESR阳性率与RPR滴度无明显相关性。
　　结论：联合检测CRP、WBC和ESR,能更好地反映以眼病为主要症状的梅毒患者的感染情况,对病情评估及监测具有一定的辅助性作用。

Clinical value of C-reactive protein, erythrocyte sedimentation rate and white blood cell count in patients with ocular syphilis

AIM: To explore the clinical value of combined detection of C-reactive protein(CRP), erythrocyte sedimentation rate(ESR)and white blood cell(WBC)count in patients with ocular syphilis.

METHODS: Dates of CRP, ESR, WBC, TPPA and RPR of 51 ophthalmopathy patients caused by syphilis and 50 normal control from Jan. 2012 to Dec. 2015 in eye hospital were recruited and analyzed statistically.

RESULTS: The positive rates of CRP, ESR and WBC of oculopathy patients were 16%, 18% and 39%, respectively, which were higher than those in the control group. In patients group, the positive rate of ESR was higher than CRP and WBC. There were no obvious relationships between RPR titers and positive ratios of CRP, WBC and ESR.

CONCLUSION: The blood level of CRP, WBC and ESR may have certain help in estimating and monitoring condition of patients with ocular syphilis.