| 老年患者血清梅毒抗体酶联免疫吸附试验假阳性结果分析 |
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| 引用本文： | 邓红艳,赫兰辉.老年患者血清梅毒抗体酶联免疫吸附试验假阳性结果分析[J].检验医学与临床,2011,8(2):151-151,153. |
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| 作者姓名： | 邓红艳 赫兰辉 |
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| 作者单位： | 成都大学附属医院检验科,成都,610081 |
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| 摘 要： | 目的对老年患者血清梅毒抗体假阳性结果及与临床的相关性进行分析和探讨。方法采用梅毒螺旋体-酶联免疫吸附试验(TP-ELISA)分别检测2 454例60岁以上老年患者和12 545例60岁以下患者血清中梅毒特异性抗体,阳性结果再用梅毒螺旋体明胶凝集试验(TPPA)复查。结果 60岁以上老年患者TP-ELISA假阳性率明显高于60岁以下患者,两组间差异有统计学意义(P<0.05)。结论试剂本身、人类宿主相关的螺旋体、基础疾病等因素是老年患者TP-ELISA易发生假阳性的重要原因,应防止产生误诊导致的医疗纠纷。
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| 关 键 词： | 梅毒 抗体 细菌 酶联免疫吸附测定 假阳性反应 老年人 |
Analysis of false positive results by ELISA analysis in elderly syphilis |
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| DENG Hong-yan,HE Lan-hui.Analysis of false positive results by ELISA analysis in elderly syphilis[J].Laboratory Medicine and Clinic,2011,8(2):151-151,153. |
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| Authors: | DENG Hong-yan HE Lan-hui |
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| Institution: | DENG Hong-yan,HE Lan-hui(Department of Laboratory,Affiliated Hospital,Chengdu University,Chengdu,Sichuan 610081,China) |
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| Abstract: | Objective To analyze the false positive results of syphilis antibodies detected by ELISA in elderly patients with syphilis and to study their relation with clinic.Methods TP-ELISA was used to detect anti-syphilis specific antibody in 2454 cases of syphilis aged more than 60 years and 12,545 cases of syphilis aged less than 60 years in our hospital from January 2007 to January 2010,those with positive results were redetected by TPPA.Results The false-positive rate of ELISA-TP in the patients aged over 60 was... |
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| Keywords: | syphilis antibodies bacterial enzyme-linked immunosorbent assay false positive reactions aged |
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