晚期早产儿近期呼吸系统并发症高危因素分析

目的 探讨晚期早产儿发生近期呼吸系统并发症的危险因素.方法 选取2011年1月至2014年12月我院收治的112例发生了近期呼吸系统疾病的晚期早产儿为观察组,随机选取同期收治的112例未发生此类疾病的晚期早产儿为对照组,分别对两组患儿的临床资料进行分析,筛选出晚期早产儿发生近期呼吸系统并发症的危险因素.结果 单因素分析结果显示,晚期早产儿发生近期呼吸系统并发症与妊娠高血压综合征、前置胎盘、胎盘早剥、母孕晚期发热、胎膜早破、羊水污染、宫内窘迫以及出生时有窒息史、小于胎龄儿、剖宫产、多胎率、脓毒血症有关(P<0.05).将上述因素纳入多元Logistic回归分析显示,母孕晚期发热、胎膜早破、宫内窘迫、剖宫产、多胎率、有窒息史、脓毒血症,是晚期早产儿发生近期呼吸系统并发症的危险因素(P<0.05),具有预警功能.结论 尽早对晚期早产儿近期呼吸系统并发症各危险因素进行有效监测与随访,可及时对患儿进行合理的干预,从而有效降低晚期早产儿近期呼吸系统疾病的发生率与死亡率.

Analysis on risk factors of early respiratory complications in late preterm infants

Objective To explore the risk factors of early respiratory complications in late preterm infants. Methods A total of 112 late preterm infants diagnosed with early respiratory complications were collected as the re-search group. At the same time, 112 late preterm infants without early respiratory complications were selected as the con-trol group. The clinical data was analyzed between the two groups in order to identify the risk factors of early respiratory complications in late preterm infants. Results Single factor analysis showed that the related factors of early respiratory complications in late preterm infants included the pregnancy-induced hypertension syndrome, placenta previa, placental abruption, maternal fever during the late pregnancy, premature rupture of membranes, contamination of amniotic fluid, fetal intrauterine distress, asphyxia, small for gestational age infant, cesarean delivery, incidence of multiple pregnancy and neonatal sepsis (P<0.05). Multivariate logistic regression analysis of the above indexes revealed that maternal fever during the late pregnancy, premature rupture of membranes, fetal intrauterine distress, cesarean delivery, incidence of multiple pregnancy, asphysia, and neonatal sepsis were the risk factors for early respiratory complications in late preterm infants (P<0.05), which have early warning function. Conclusion It is important to focus the risk factors for effective monitoring and follow-up, which could provide timely reasonable intervention for neonates and reduce the incidence of early respiratory complications in late preterm infants and the neonatal mortality.