前列腺增生合并前列腺炎的临床研究

目的探讨前列腺增生(BPH)合并前列腺炎(CP)的临床特点及其相互关系。方法对我科于2000年1月～2009年12月收治的287例BPH合CP患者进行回顾性分析。根据有无合并CP,将所有患者分为CP组(124例)和非CP组(163例),比较两组患者年龄、EPS白细胞数量、前列腺特异性抗原(PSA)、前列腺体积、国际前列腺症状评分(IPSS)及生活质量评分(QOL)的差异。然而根据有无接受抗CP治疗,进一步将CP组患者分为治疗组(73例)和对照组(51例),比较两组治疗前后IPSS和QOL评分的变化。结果与非CP组相比,CP组患者发病年龄更迟、血清PSA值更高、前列腺体积更大、IPSS及QOL评分更高(均P0.05),但EPS白细胞计数两组比较,差异无统计学意义(P0.05)。治疗组治疗后,IPSS及QOL评分明显下降(P0.05),而对照组治疗后IPSS及QOL评分未明显改善(P0.05)。结论 BPH常合并CP;与单纯BPH相比,BPH合并CP具有发病年龄迟、血清PSA更高、临床症状更为严重的特点;在常规BPH治疗的同时予以抗CP治疗,可取得更为显著的疗效。

A clinical analysis of benign prostastic hyperplasis associated with chronic prostatitis

Objective To study the clinical chracteristics of benign prostatic hyperplasia（BPH） complicated by chronic prostatitis（CP） and evaluate the relationship between BHP and CP.Methods From January 2000 to December 2009,287 cases with BPH associated with CP were analyzed retrospectively.A total of 287 BPH patients were divided into CP group（n=124） and non-CP group（n=163）.The age,EPS WBC counts,PSA,prostate volumn,IPSS and quality of life（QOL） were compared between the two groups.For patients in CP group,73 cases underwent CP treatment and 51 did not underwent CP treatment.The score of IPSS and QOL were compared before and after treatment in the two subgroups.Results As compared with non-CP group,the patients in CP group had elderly age,higher serum PSA level,bigger prostatic volume and higher IPSS and QOL scores（all P0.05）.EPS WBC counts was similar between the two groups（P0.05）.IPSS and QOL scores were decreased in the cases receiving CP treatment（P0.05） and did not significantly change in the cases not receiving CP treatment（P0.05）.Conclusions Many BPH patients were accompanied by CP.As compared with simple BPH,the patients associated with CP have elderly age,higher serum PSA and more serious symptoms.Adding anti-CP treatment to routine BPH therapy may have better therapeutic outcomes.