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复方甘草酸苷治疗抗肿瘤药导致肝损害的疗效观察
引用本文:郑滢,宋方闻,庄学龙,吴悦义. 复方甘草酸苷治疗抗肿瘤药导致肝损害的疗效观察[J]. 中国药房, 2005, 16(3): 207-208
作者姓名:郑滢  宋方闻  庄学龙  吴悦义
作者单位:1. 广东汕头大学医学院附属肿瘤医院,汕头市,515031
2. 广州医学院南大学院,广州市,510320
摘    要:目的 :观察复方甘草酸苷治疗抗肿瘤药导致肝损害的疗效。方法 :将60例应用抗肿瘤药导致肝功能损害的患者随机分成治疗组 (32例 )和对照组 (28例 ) ,治疗组在对照组用药基础上加用复方甘草酸苷。结果 :治疗组在丙氨酸氨基转移酶、天门冬氨酸氨基转移酶、总胆红素的改善程度上均明显优于对照组 (P<0.01)。结论 :复方甘草酸苷有很好的保肝降酶、抗炎、免疫调节作用 ,未见不良反应 ,用药安全 ,推荐用于治疗抗肿瘤药导致的肝损害。

关 键 词:复方甘草酸苷  抗肿瘤药  肝损害  疗效
文章编号:1001-0408(2005)03-0207-02
修稿时间:2004-10-27

Clinical Effects of SNMCTM on Liver Injury Induced by Anti- Tumor Medicine
ZHENG Ying,ZHUANG Xuelong,WU Yueyi. Clinical Effects of SNMCTM on Liver Injury Induced by Anti- Tumor Medicine[J]. China Pharmacy, 2005, 16(3): 207-208
Authors:ZHENG Ying  ZHUANG Xuelong  WU Yueyi
Abstract:OBJECTIVE:To observe the clinical effects of Stronger Neo-Minophagen C(SNMC)in the treatment of liver function damage caused by anti-tumor medicine.METHODS:60cases of liver injury caused by anti-tumor medicine were randomly divided into the treatment group(32cases)and the control group(28cases).SNMC injection was given in the treatment group as a supplement to the primary therapy in the control group.RESULTS:The treatment group with SNMC showed significantly greater improvement than the control group in the liver functions(ALT,AST,T.BIL)(P<0.01).CONC_ LUSION:SNMC is effective for liver function damage caused by anti-tumor medicine for its protective,anti-inflammatory,and immunity-regulatory function.SNMC is also a secure medicine with less side effects and therefore is recommendable for treatment of liver injury caused by anti-tumor medicine.
Keywords:Stronger Neo-Minophagen C(SNMC)  Anti-tumor medicine  Liver injury  Clinical effects
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