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Dimethyl celecoxib as a novel non-cyclooxygenase 2 therapy in the treatment of non-small cell lung cancer
Authors:Backhus Leah M  Petasis Nicos A  Uddin Jasim  Schönthal Axel H  Bart Robert D  Lin Yuanguang  Starnes Vaughn A  Bremner Ross M
Affiliation:a Department of Cardiothoracic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, Calif
b Department of Chemistry, University of Southern California, Los Angeles, Calif
c Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, Calif.
Abstract:
Keywords:COX-2, cyclooxygenase 2   DMC, 2,5-dimethyl celecoxib   FBS, fetal bovine serum   FITC, fluorescein isothiocyanate   IL, interleukin   MMP, matrix metalloproteinase   MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium, inner salt   NSCLC, non-small cell lung cancer   PBS, phosphate-buffered saline   PGE2, prostaglandin E2   RPMI, Roswell Park Memorial Institute
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