| 复方新诺明片的溶出度测定 |
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| 引用本文： | 金京顺,毕鉴舫,吴兵.复方新诺明片的溶出度测定[J].中国医药工业杂志,1987(12). |
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| 作者姓名： | 金京顺 毕鉴舫 吴兵 |
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| 作者单位： | 吉林省药品检验所，吉林省药品检验所，吉林省药品检验所 |
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| 摘 要： | 采用双波长法和吸收度加和性原理,直接测定复方新诺明片中磺胺甲基异(口恶)唑和甲氧苄氨嘧啶的溶出度。此法快速、简便。磺胺甲基异(口恶)唑平均回收率为100.9%,甲氧苄氨嘧啶平均回收率为99.69%。变异系数分别为0.76%和1.90%。
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| 关 键 词： | 溶出度测定 复方新诺明片 |
DISSOLUTION TEST OF CO-TRIMOXAZOLE TABLETS |
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| Authors: | JIN Jing-shun BI Jian-fang WU Bing |
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| Abstract: | The dissolution rate of sulfamethoxazole(1)and trimethoprim(2)in co-trimoxazole tablets was determined directly by spectrophotometry usingthe dual-wavelength method and according to the additive property of absorption.This method was rapid and simple.The average recovery of 1 was 100.9% and2 was 99.69%.The coefficients of variation were 0.76% and 1.90%,respectively. |
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| Keywords: | dissolution test co-trimoxazole tablets |
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