Therapeutic potential of PRL-3 targeting and clinical significance of <Emphasis Type=Italic>PRL-3</Emphasis> genomic amplification in gastric cancer期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancer

Authors:	Akira Ooki Keishi Yamashita Shiro Kikuchi Shinichi Sakuramoto Natsuya Katada Mina Waraya Hiroshi Kawamata Hiroshi Nishimiya Kazunori Nakamura Masahiko Watanabe

Affiliation:	(1) Department of Surgery, Kitasato University Hospital, Kitasato 1-15-1, Sagamihara 228-8555, Kanagawa, Japan

Abstract:	Background Phosphatase of regenerating liver-3 (PRL-3) has deserved attention as a crucial molecule in the multiple steps of metastasis. In the present study, we examined the mechanisms regulating PRL-3 expression, and assessed the clinical potential of PRL-3-targeted therapy in gastric cancer.

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