| 用精子头部银染法观察几种雄性抗生育因子的作用 |
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| 引用本文： | 叶惟三,邓艳春.用精子头部银染法观察几种雄性抗生育因子的作用[J].解剖学报,1992,23(3):290-293. |
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| 作者姓名： | 叶惟三 邓艳春 |
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| 作者单位： | 中国医学科学院基础医学研究所，中国医学科学院基础医学研究所，中国医学科学院基础医学研究所，中国医学科学院基础医学研究所，中国医学科学院基础医学研究所 北京 100005，北京 100005，北京 100005，北京 100005，北京 100005 |
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| 摘 要： |
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| 关 键 词： | 诱变 精子头部异常 雷公藤多甙 |
THE POSSIBLE MUTAGENESIS OF SEVERAL MALE ANTIFERTILITY AGENTS IN SPERM HEAD ANOMALIES |
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| Ye Weisan,Deng Yanchun,Huang Yuling,Han Yuhua,Xue Shepu.THE POSSIBLE MUTAGENESIS OF SEVERAL MALE ANTIFERTILITY AGENTS IN SPERM HEAD ANOMALIES[J].Acta Anatomica Sinica,1992,23(3):290-293. |
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| Authors: | Ye Weisan Deng Yanchun Huang Yuling Han Yuhua Xue Shepu |
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| Abstract: | Mutagenesis of several male contraceptives in sperm bead anomalies was investigated. Results show that glycosides of tripterygium wilfordii hook (GTW) and its monomer T13, microwave induce sperm head anomalies. However, gossypol and monomer T4 and GTW do not induce sperm head anomalies. Adult male mice and rats were given orally GTW, monomer T4, T13 and gossypol. These chemical agents were delivered in 1% methylcellulose. Result indicated that frequency of abnormal sperm heads in GTW, T13 groups were significantly increased, while frequency of abnormal sperm heads in T4 and gossypol-treated animals were similar to that of normal controls. When male mice were exposed to microwaves of 0.5 kW for 1-2 min, for five weeks abnormal shape of spermatozoa could be found. |
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| Keywords: | Clastogenicity Sperm head anomalies Glycosides of tripterygium wilfordii hook Monomer T4 Monomer T13 Microwave |
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