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涎腺淋巴上皮癌临床病理观察
引用本文:张伟,唐仁泉,刘媛媛,刘东威,张学义.涎腺淋巴上皮癌临床病理观察[J].现代肿瘤医学,2010,18(2).
作者姓名:张伟  唐仁泉  刘媛媛  刘东威  张学义
作者单位:抚顺矿务局总医院病理科,辽宁,抚顺,113008
摘    要:目的:探讨涎腺淋巴上皮癌的临床病理学特征和鉴别诊断.方法: 对5例涎腺淋巴上皮癌的临床特征、组织学形态和免疫学表型进行观察.结果: 3例肿瘤发生于耳垂下,2例发生于下颌下区.临床主要表现为局部包块,活动度差,伴有疼痛.组织学特点为肿瘤细胞较大,多角形、卵圆形,细胞核泡状,肿瘤细胞呈片状、岛状、索条状,间质为成熟的淋巴细胞和浆细胞.免疫组化:5例肿瘤细胞CK(pan)、EMA、EBV均为(+);而S-100、CgA、CD68、LCA、Vimentin、SMA均为(-);间质细胞CD3、CD20、CD43均为部分 (+). 结论: 涎腺淋巴上皮癌非常少见,是一种分化差,但是预后尚可的肿瘤,确诊依赖组织学和免疫组化检测.手术广泛全切和术后辅助放疗是本病的最佳治疗措施.

关 键 词:淋巴上皮癌  涎腺  临床病理

Lymphoepithelial carcinoma of salivary gland:a cinicopathologic observation
ZHANG Wei,TANG Ren-quan,LIU Yuan-yuan,LIU Dong-wei,ZHANG Xue-yi.Lymphoepithelial carcinoma of salivary gland:a cinicopathologic observation[J].Journal of Modern Oncology,2010,18(2).
Authors:ZHANG Wei  TANG Ren-quan  LIU Yuan-yuan  LIU Dong-wei  ZHANG Xue-yi
Institution:ZHANG Wei,TANG Ren-quan,LIU Yuan-yuan,LIU Dong-wei,ZHANG Xue-yi Department of pathology,the General Hospital of Fushun Mining Group,Fushun 13008,China.
Abstract:Objective:To investigate the clinicopathological features of lymphoepithelial carcinoma of salivary gland and its diagnosis.Methods: Clinical,morphologic and immunohistochemical representations were described in 5 cases of lymphoepithelial carcinoma of salivary gland.Results: The tumors were located at the underneath lobulus auricular subcutaneous in 3 cases,underneath lower jaw subcutaneous in 2 cases.The major clinical manifestations were focal phyma,range of the motion was bad and pain.Microscopically,th...
Keywords:lymphoepithelial carcinoma  salivary gland  clinical pathological  
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