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Malignant melanoma of the choroid in an 11-month-old infant.
Authors:H Fledelius  A M Land
Abstract:A malignant melanoma of the choroid was observed in an 11-month-old fair-skinned Danish boy - one of the youngest cases ever published. There was no evidence of pre-existing melanosis of eyes or skin. The tumour showed histopathologically a typical "adult" pattern and was classified as a mixed tumour. The melanin content was marked. In some earlier reports on uveal tumours within the first year of life, pigmentation was sparse or lacking; a hypothesis has therefore previously been advanced: That melanomas are unable to produce melanin so early in life. The present case renders proof against this hypothesis.
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