| 主视眼的形成机制及临床研究进展 |
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| 引用本文： | 万博综述,鲍永珍审校. 主视眼的形成机制及临床研究进展[J]. 眼科研究, 2013, 0(12): 1169-1172 |
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| 作者姓名： | 万博综述 鲍永珍审校 |
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| 作者单位： | 北京大学人民医院眼科视觉损伤与修复教育部重点实验室, 100044 |
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| 摘 要： | 自Porta提出主视眼的概念以来，有关此领域的研究在不断深入，特别是近十年来通过大脑视皮层的神经生理学、分子生物学的研究证实，主视眼的形成与主视眼柱、N一甲基一D一门冬氨酸（NMDA）受体、aCaMKll、神经突触以及基因有关。目前，眼科临床对主视眼的认识逐渐加深，并开始应用于验光配镜、准分子激光手术以及白内障手术等领域。就近年来主视眼的形成机制和临床应用进展进行综述。
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| 关 键 词： | 主视眼 主视眼柱 立体视 年龄相关性白内障 单眼视 |
Advance in mechanism and clinical application of ocular dominance |
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| Affiliation: | WAN Bo, BAO Yong-zhen. Key laboratory of Vision Loss and Restoration of Ministry of Education, Department of Ophchalmvlogy, Peking University People Hospital, Peking University, Beijing 100044, China |
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| Abstract: | The researches on ocular dominance have been continuing deeply last decade years since the concept was first described by means by Porta in 1593. Based on the neurophysiology and molecular biology, it is confirmed that the procedure of ocular dominance involves sublayer 4C of the visual cortex, N-Methyl-D-aspartate （NMDA）-receptor, a-calmodulin kinase 1/ （aCaMK 11 ）, synapses and about candidate gens. Meanwhile, ocular dominance theory plays an important guiding role in optometry, laser-assisted in situ keratomileusis and cataract operation. In this review ,the mechanism and clinical application of ocular dominance were summarized. |
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| Keywords: | Ocular dominance Ocular dominance columns Stereopsis Age-related cataract Monovision |
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