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| HPLC法测定舒心宁片中芍药苷的含量 | |
| 引用本文： | 杨翰,王海宁,刘丰丰. HPLC法测定舒心宁片中芍药苷的含量[J]. 中国药房, 2007, 18(24): 1885-1887 |
| 作者姓名： | 杨翰 王海宁 刘丰丰 |
| 作者单位： | 1. 贵阳市第二人民医院,贵阳市,550005 2. 贵州省药品检验所,贵阳市,550004 3. 贵阳医学院附属医院,贵阳市,550004 |
| 摘 要： | 目的:建立以高效液相色谱法测定舒心宁片中芍药苷含量的方法。方法:色谱柱为Kromasil C18(250mm×5.0mm,5μm),流动相为甲醇-水(35:65),流速为1.0mL.min-1,检测波长为230nm,柱温为30℃。结果:芍药苷进样量在0.1616～1.4544μg范围内与峰面积积分值呈良好的线性关系(r=0.9998);平均回收率为100.56%,RSD=1.50%(n=6)。结论:本法简便、准确、精密度高、重现性好,可用于该制剂的质量控制。 |
| 关 键 词： | 高效液相色谱法 舒心宁片 芍药苷 含量测定 |
| 文章编号： | 1001-0408（2007）24-1885-03 |
| 收稿时间： | 2007-01-03 |
| 修稿时间： | 2007-01-032007-04-27 |
Determination of Peoniflorin in Shuxinning Tablets by HPLC |
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| YANG Han,WANG Haining,LIU Fengfeng. Determination of Peoniflorin in Shuxinning Tablets by HPLC[J]. China Pharmacy, 2007, 18(24): 1885-1887 | |
| Authors: | YANG Han WANG Haining LIU Fengfeng |
| Abstract: | OBJECTIVE:To establish a HPLC method for the determination of Peoniflorin in Shuxinning tablets.METHODS:The determination was performed on Kromasil C18(250mm× 5.0mm,5μ m) column with column temperature set at 30℃.The mobile phase consisted of methanol-water(35:65) with flow rate of 1.0mL· min-1.The detection wavelength was set at 230nm.RESULTS:Good linear relation was achieved when sample size of Peoniflorin ranged at 0.161 6～ 1.454 4μg(r=0.999 8).The average recovery was 100.56%,RSD=1.50%(n=6).CONCLUSION:The method was simple,accurate,precise,and with high resolution,and it can be used for the quality control of Shuxinning tablets. |
| Keywords: | HPLC Shuxinning tablets Peoniflorin Content determination |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |