经颅超声造影在大脑中动脉狭窄定位及定量诊断中的初步应用

目的探讨经颅超声造影(CE-TCCS)在大脑中动脉(MCA)狭窄闭塞病变诊断中的应用价值。方法对86例临床疑似大脑中动脉狭窄闭塞的患者分别行经颅彩色多普勒超声(TCCS)及经颅超声造影检查,比较造影前后大脑中动脉狭窄显示率、定位狭窄部位、评价狭窄程度,并与核磁共振血管成像和(或)数字减影血管造影检查结果进行对照。结果经核磁共振血管成像和(或)数字减影血管造影显示,86例中98支大脑中动脉狭窄,经颅彩色多普勒超声诊断狭窄79支(79/98,80.6%),经颅超声造影诊断狭窄98支(98/98,100%),其中M1段狭窄68支,M2段狭窄30支;经颅超声造影对大脑中动脉狭窄定位诊断准确率为94.9%(93/98),不同程度的大脑中动脉狭窄表现不同。结论经颅超声造影能够准确诊断大脑中动脉狭窄,狭窄部位定位准确,对狭窄程度的评价有一定作用,有望成为大脑中动脉狭窄闭塞病变首选的筛查方法。

The primary application of transcranial contrast enhanced ultrasound in the stenosis and occlusion disease of middle cerebral artery

Objective To explore the value of contrast-enhanced transcranial color-coded sonography(CE-TCCS) in stenosis and occlusion of middle cerebral artery(MCA). Methods Tracranial color-coded sonogrphy(TCCS) was performed in 86 patients who were firstly diagnosed with stenosis and occlusion of MCA before and after injection of ultrasound contrast agent. The display rate of intracranial arteries was compared before with after injecion contrast agent. The blood flow characteristics of transcranial contrast-enhanced...