痛经女大学生中子宫内膜异位症患病情况调查

目的:探讨子宫内膜异位症在有痛经的青春期女大学生中的患病情况.方法:通过问卷调查收集数据,对有痛经症状的患者进行腹部超声及CA125检查,必要时进行腹腔镜手术,对于拒绝腹腔镜手术的患者进行MRI 检查,以确定内异症的患病率.结果:423人接受了问卷调查,有较严重痛经症状者(对非甾体类止痛药及激素类药无效)占46.81%(n=198).痛经患者经腹部彩超检查有内异症阳性报道者占26.26%(n=52),在这些患者中有61.53%接受腹腔镜治疗(n=32),其中28例(53.85%)术后病理检查报告确诊为子宫内膜异位症.腹部彩超检查可疑为内异症的患者(n=52)中,检查血清CA125,在正常范围内者占51.92%(n=27),高于正常者48.08%(n=25),CA125正常者中有恶心呕吐症状者6人,有尿痛症状者7人,有里急后重及排便痛苦者8人,没有上述症者6人;CA125高于正常者出现恶心呕吐症状者4人,有尿痛症状者5人,有里急后重及排便痛苦者16人,没有上述症者0人.结论:有严重痛经症状的在校女大学生子宫内膜异位症的发生率为14.14%,临床可通过腹部B超、CA125、MRI及腹腔镜手术对患者进行早期诊断及干预,以改善预后.

An Investigation Into the Prevalence of Endometriosis in Female College Students with Dysmenorrhea

Objective: To investigate the prevalence of endometriosis in adolescent female college students with dysmenorrhea.Methods:This study collected relevant data through a questionnaire.Then patients with dysmenorrhea symtoms were given abdominal ultrosound and CA125 examination.If necessary, they would undergo laparoscopic surgery.For patients who refused laparoscopic surgery, they were checked with MRI to determine the prevalence of endometriosis.Results: A total of 423 female college students were asked to complete the questionnaire.Of these people, patients with severe dysmenorrhea symptoms(invalid to nonsteroidal painkillers and hormone drugs) accounted for 46.81%(n=198).Patients with dysmenorrhea who were reported endometriosis after abdominal color Doppler ultrasound examination accounted for 26.26%(n=52).In these patients,61.53% received laparoscopic treatment (n=32),28 of which (53.85%) were diagnosed with endometriosis.After abdominal color Doppler ultrasound examination,patients with suspected endometriosis(n=52) who were checked the serum CA125 were 51.92%(n=27) in the normal range,48.08%(n=25) higher than that in the normal group (n=25).Among patients with normal CA125,6 people had nausea and vomiting symptoms,7 had symptoms of dysuria,8 experienced tenesmus and pain after the defecation and 6 people had no above symptoms.Among those with higher CA125,4 people had nausea and vomiting symptoms,5 had symptoms of dysuria,16 experienced tenesmus and pain after the defecation and the number of patients without above symptoms was zero.Conclusion:The incidence of endometriosis in female college students with severe dysmenorrhea was 14.14%.Therefore,to improve the prognosis,early diagnosis and intervention should be made through abdominal ultrasonography,CA125,MRI and laparoscopic surgery.