| 聚羟基磷酸钙钠的骨细胞相容性体外研究 |
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| 引用本文： | 唐昭,陈治清,刘卫军. 聚羟基磷酸钙钠的骨细胞相容性体外研究[J]. 生物医学工程学杂志, 2000, 17(2): 122-124,128 |
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| 作者姓名： | 唐昭 陈治清 刘卫军 |
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| 作者单位： | 1. 暨南大学,医学院口腔系,广州,510632
2. 华西医科大学,口腔医学院材料学教研室,成都,610041 |
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| 基金项目： | 国家自然科学基金!39330090 |
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| 摘 要： | 聚羟基磷酸钙钠（Ｈｙｄｒｏｘｙｌ ｐｏｌｙｃａｌｃｉｕｍｓｏｄｉｕｍ ｐｈｏｓｐｈａｔｅ，ＨＰ）是一种新的人人体硬组织替代。本实验选用Ｓ．Ｄ乳鼠颅顶细胞，采用体外细胞培养技术，从细胞水平评价聚羟基磷酸钙钠的骨细胞相容性体外研究。结果表明细胞在ＨＰ表面正常粘附、伸展、增殖，具有良好的细胞附着形态及细胞增殖率，其增殖速度较羟基磷灰石，生物玻璃陶瓷快，表明ＨＰ更有利于细胞的粘附生长，容易形成早期骨性结合
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| 关 键 词： | 成骨细胞 生物相容性 硬组织替代材料 HP |
Study on Osteocompatibility of Hydroxyl Polycalcium Sodium Phosphate in vitro |
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| Tang Zhao,Chen Zhiqing,Liu Weijun. Study on Osteocompatibility of Hydroxyl Polycalcium Sodium Phosphate in vitro[J]. Journal of biomedical engineering, 2000, 17(2): 122-124,128 |
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| Authors: | Tang Zhao Chen Zhiqing Liu Weijun |
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| Affiliation: | Department of Stomatology, Medical College, Jinan University, Guangzhou 510632. |
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| Abstract: | Hydroxyl polycalcium sodium phosphate(HP) is a new substitute material for human hard tissues.The isolated rat osteoblasts from the parietal and frontal bones of 1-3d SpragueDawley rats were used to estimate the osteocompatibility of HP in this study. The effects of the materials on cell morphology,growth and proliferation were determined. The result showed that rat osteoblasts could attach,spread and proliferate on HP as normal cells.The proliferation of cells on HP was more favour able to the adhesion and proliferation of rat osteoblasts and could form osteointergration early. |
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| Keywords: | Osteoblasts Biocompatibility Subsititute materials for hard tissues |
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