复方嗜酸乳杆菌片联合光疗、抚触治疗新生儿黄疸的临床疗效及其对胆红素水平的影响

目的:探讨药物治疗联合光疗、抚触对新生儿黄疸胆红素水平及临床症状的影响。方法:选取我院2017年2-5月收治的84例黄疸新生儿,采用随机抽样法分为观察组和对照组各42例。对照组采用蓝光+抚触治疗,观察组采用药物联合光疗+抚触治疗,比较两组新生儿的胆红素水平及临床症状等变化。结果:观察组的有效率高于对照组,不良反应较对照组少,差异有统计学意义(P<0.05)。观察组的黄疸消退时间、胎便转黄时间、首次排便时间短于对照组,差异有统计学意义(P<0.01)。观察组治疗后C反应蛋白、血清总胆红素、间接胆红素低于对照组,差异有统计学意义(P<0.01)。结论:药物联合光疗+抚触能够显著降低新生儿黄疸的胆红素水平,改善临床症状,缩短病程,减少不良反应,值得推广。

Compound Lactobacillus Acidophilus Tablets Combined with Phototherapy and Touch Therapy in the Treatment of Neonatal Jaundice and Its Effects on Bilirubin Levels

Objective: To probe into the effects of drug therapy combined with phototherapy and touch therapy on neonatal jaundice bilirubin and clinical symptoms. Methods: Eighty-four neonates with jaundice bilirubin admitted into our hospital from Feb. to May 2017 were extracted to be divided into observation group and control group according to the random extraction, with 42 cases in each group. The control group was given blue-ray and touch therapy, while the observation group received combination of drugs, phototherapy and touch therapy. Changes of neonatal jaundice bilirubin and clinical symptoms of two groups were compared. Results: The total effective rate of observation group was higher than that of control group, and the adverse drug reactions of observation group were less than those of control group, the difference was statistically significant (P<0.05). The disappearance time of jaundice, time of defecation of fetus and time of first defecation were shorter in the observation group than in the control group, and the difference was statistically significant (P<0.01). After treatment, C-reactive protein, serum total bilirubin and indirect bilirubin in observation group were lower than those in control group, and the differences were statistically significant (P<0.01). Conclusion: Combination of drugs, phototherapy and touch therapy can significantly reduce the neonatal jaundice bilirubin, improve the clinical symptoms, shorten the course of disease and reduce the adverse drug reactions; it is worthy of promotion.