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振动排痰辅助常规雾化治疗儿童喘息性支气管炎疗效观察
引用本文:李小莉,沈剑,郑绪阳. 振动排痰辅助常规雾化治疗儿童喘息性支气管炎疗效观察[J]. 儿科药学杂志, 2018, 24(12): 26-29
作者姓名:李小莉  沈剑  郑绪阳
作者单位:浙江大学医学院附属杭州市第一人民医院,浙江杭州 310003
摘    要:目的:探讨振动排痰在儿童喘息性支气管炎治疗中的应用价值。方法:选择2017年6月至2018年1月我科收治的喘息性支气管炎的患儿60例,按随机数表法分为对照组和观察组各30例,均给予常规对症治疗,减少气道分泌物,缓解咳嗽,并酌情给予吸氧及抗感染治疗。对照组患儿给予常规雾化方案(吸入用异丙托溴铵溶液+吸入用布地奈德混悬液) 治疗,观察组患儿在对照组雾化方案的基础上运用振动排痰辅助治疗,观察并比较两组患儿的临床疗效、临床症状消失时间及治疗前后的肺功能指标。结果:观察组患儿总有效率为96.67%,高于对照组的76.67% (P<0.05);咳嗽缓解、喘息缓解、肺部啰音消失时间及住院时间均短于对照组(P均<0.05);治疗后FEV1、FVC、FEV1/ FVC、PEF均高于对照组(P均<0.05)。结论:振动排痰辅助常规雾化治疗儿童喘息性支气管炎疗效确切,安全可靠,是一种增效的治疗方式,值得临床推广应用。

关 键 词:阿奇霉素;哮喘样症状;儿童;预防

Vibration Expectoration Combined with Aerosol Inhalation in the Treatment of Asthmatic Bronchitis
Li Xiaoli,Shen Jian,Zheng Xuyang. Vibration Expectoration Combined with Aerosol Inhalation in the Treatment of Asthmatic Bronchitis[J]. Journal of Pediatric Pharmacy, 2018, 24(12): 26-29
Authors:Li Xiaoli  Shen Jian  Zheng Xuyang
Affiliation:Hangzhou the First People''s Hospital Affiliated to Zhejiang University School of Medicine, Zhejiang Hangzhou 310003, China
Abstract:Objective: To investigate the application value of vibration expectoration in the treatment of asthmatic bronchitis in children. Methods: A total of 60 children with asthmatic bronchitis admitted into our department from Jun. 2017 to Jan. 2018 were extracted to be divided into observation group and control group via the random number table, with 30 cases in each group. All patients were given conventional symptomatic treatment, such as reducing airway secretions, relieving cough, and giving oxygen and anti-infective treatment as appropriate. Children in the control group were treated with conventional aerosol inhalation scheme (ipratropium bromide solution for inhalation + budesonide suspension for inhalation), and the observation group received vibration expectoration on the basis of the control group. The clinical efficacy, disappearance time of clinical symptoms and lung function indexes before and after treatment were observed and compared between two groups. Results: The total effective rate was 96.67% in the observation group, higher than 76.67% in the control group (P <0.05). The cough relief time, wheezing relief time,disappearance time of lung rales and length of stay in the observation group were shorter than those in the control group (P<0.05). And FEV1, FVC, FEV1/ FVC and PEF in the observation group were higher than those in the control group (P<0.05). Conclusion: Vibration expectoration combined with aerosol inhalation in the treatment of asthmatic bronchitis in children is efficacy, safety and reliability. It is a synergistic treatment and worthy of clinical application.
Keywords:aerosol inhalation   vibration expectoration   asthmatic bronchitis
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