海南地区百岁老人网织红细胞各项参数特点

目的 调查分析海南地区百岁老人网织红细胞各项参数特点.方法 选取百岁老人68例,18～83岁健康人群129例,采用Sysmex XT-4000i型全自动血液细胞分析仪分析网织红细胞五项参数:网织红细胞绝对值(RET#)、网织红细胞百分率(RET％)、高荧光网织红细胞百分率(HFR％)、中荧光网织红细胞百分率(MFR％)、低荧光网织红细胞百分率(LFR％).结果 百岁老人HGB[(113.38±15.09)g/L]、RET％[(1.04±0.37)]、RET#[(41.37±15.04)×109/L]、MCH[(28.43±2.59)pg]、MCHC[(316.00±9.5)g/L]和RBC[(4.00±0.50)×1012/L]均低于健康成年人,差异均有统计学意义(P<0.05);HFR％(0.34±0.43)、MFR％(3.43±2.50)、LFR％(96.23±2.67)和MCV(89.94±7.01)同健康成年人比较差异均无统计学意义(P>0.05);百岁老人HGB仅与RET#存在弱相关性(r=0.298,P<0.05),而与RET％、RET#、HFR％、MFR％和MFR％均无相关性(P>0.05).结论 百岁老人骨髓造血能力衰退,HGB和网织红各项参数均低于成年人群,需独立制定相应参考范围才能与百岁老人疾病诊断匹配.

Parameters characteristics of reticulocyte in Hainan centenarians

Objective To investigate and analyze the Hainan centenarians'reticulocyte parameters characteris-tics. Methods Sixty-eight centenarians and 129 healthy adults aged from 18 to 83 was selected, and five reticulocyte parameters were analyzed by Sysmex XT-4000i automatic blood cell analyzer, including reticulocyte percentage (RET％), reticulocyte absolute value (RET#), high fluorescent reticulocyte percentage (HFR％), middle fluorescent retic-ulocyte percentage (MFR％), and low fluorescent reticulocyte percentage (LFR％). Results The HGB, RET％, RET#, MCH, MCHC and RBC in Hainan centenarians were respectively (113.38±15.09) g/L, (1.04±0.37), (41.37±15.04)×109/L, (28.43±2.59) pg, (316.00±9.5) g/L and (4.00±0.50)×1012/L, significantly lower than those in the healthy adults (P<0.05);The HFR％, MFR％, LFR％, and MCV in Hainan centenarians were (0.34±0.43), (3.43±2.50), (96.23±2.67) and (89.94± 7.01), which showed no statistically significant differences with those of the healthy adults (P>0.05); HGB only had weak correlation with RET# in the centenarians (r=0.298,P<0.05), but it showed no correlation with RET％, RET#, HFR％ and MFR％ (P>0.05). Conclusion Centenarians have hypofunction in bone marrow hematopoiesis, and their HGB and reticulocytes are lower than those of adults. It is necessary to formulate the appropriate reference independent-ly to match the disease diagnosis of centenarians.