T2*mapping定量评估早期骨关节炎半月板与软骨的相关性

目的 利用T2*mapping评估早期膝关节骨性关节炎(OA)的软骨与半月板并分析半月板退变与软骨损伤的相关性.方法 收集2016年8～11月在重庆医科大学附属永川医院骨科就诊的65例早期OA患者,均行常规MR、多回波梯度回波T2*mapping扫描.并测量所有患者内、外侧半月板损伤在Stoller分级中软骨与半月板T2*值.结果 内侧半月板损伤中,MM 1级组T2*值(10.33±2.82)ms]高于MM 0级(8.95±1.73)ms],MM 2、3级组T2*值(13.31±2.27)ms]均高于MM 0级组、MM 1级组,差异均有统计学意义(P<0.05);外侧半月板损伤中,MM 1级组T2*值(10.63±2.58)ms]高于MM 0级(8.65±2.61)ms],MM 2、3级组T2*值(13.59±2.41)ms]均高于MM 0级组、MM 1级组,差异均有统计学意义(P<0.05);内侧半月板损伤中,2、3级组股骨内侧踝(MFC)与胫骨内侧(MT)的T2*值均高于0级组、1级组的T2*值,外侧半月板损伤中,2、3级组胫骨外侧(LT)高于0级、1级组软骨单元T2*值,差异均有统计学意义(P<0.05);内侧半月板T2*值与内侧股骨髁、内侧胫骨软骨单元T2*值呈正相关(r=0.45,r=0.56);外侧半月板T2*值与外侧胫骨软骨单元T2*值呈正相关(r=0.40).结论 T2*mapping能够定量监测OA半月板退变,OA半月板损伤与邻近软骨损伤呈正相关.

Quantitative assessment of the correlation between meniscus and cartilage in early osteoarthritis with T2* mapping

Objective To assess the correlation between meniscus and cartilage in early osteoarthritis (OA) with T2*mapping. Methods A total of 65 patients with early OA, who admitted to Department of Radiology of Yong-chuan Hospital of Chongqing Medical University and underwent routine conventional MR sequences and mutil-echo gra-dient echo sequence for T2*mapping, were selected as the research subjects. The T2*values of menicus and cartilage in Stoller grade score system for internal and lateral meniscus injury of the patients were measured. Results For medial meniscal tear, the T2* value of medial meniscus (MM) 1 group was (10.33 ± 2.82) ms, which was significantly higher than (8.95±1.73) ms of MM 0 group (P<0.05). The T2*value of MM 2 and 3 group was (13.31±2.27) ms, which was sig-nificantly higher than the T2*value of MM 0 and MM 1 group (P<0.05). For lateral meniscal tear, the T2*value of MM 1 group was (10.63 ± 2.58) ms, which was significantly higher than (8.65 ± 2.61) ms of MM 0 group (P<0.05). The T2*value of MM 2 and 3 group was (13.59±2.41) ms, which was significantly higher than MM 0 and MM 1 group (P<0.05). For medial meniscal tear, the T2*value of medial femoral condyle (MFC) and medial tibial (MT) in 2 and 3 grade was sig-nificantly higher than that in 0 grade and 1 grade;For lateral meniscal tear, the T2*value of lateral meniscus (LT) in 2 and 3 grade was significantly higher than that in 0 grade and 1 grade (P<0.05). The T2*value of the medial meniscus was posi-tively correlated with the T2*values of the MFC and MT (r=0.45, r=0.56);The T2*value of the lateral meniscus (LM) was positively correlated with the T2*value of the LT (r=0.40). Conclusion T2*mapping can quantitatively monitor the meniscal degeneration in early OA. There is a positive correlation between meniscal tear and adjacent to cartilage damage.