原发性良性阵发性位置性眩晕患者前庭诱发肌源性电位检测的意义

目的：探讨检测眼肌前庭诱发肌源性电位（oVEMP）和颈肌前庭诱发肌源性电位（cVEMP）对单侧原发性良性阵发性位置性眩晕（BPPV）患者进行可能发病部位的定位诊断价值。方法：对52例单侧原发性BP-PV患者（BPPV组）和38例正常人（对照组）分别进行气导短纯音诱发的oVEMP和cVEMP检测，分析两种反射的引出率、潜伏期、振幅等数据。结果;BPPV组患侧oVEMP的引出率为46．15％，cVEMP的引出率为67．31％；其健侧oVEMP的引出率为48．08％，cVEMP的引出率为65．38％。对照组左侧oVEMP的引出率84．21％，cVEMP的引出率92．11％；右侧oVEMP的引出率为81．58％，cVEMP的引出率为94．74％。对照组双侧cVEMP和oVEMP的P1、N1潜伏期及N1-P1振幅值差异均无统计学意义。BPPV组和对照组cVEMP和oVEMP耳间振幅比及不对称率差异有统计学意义（P〈0．05）。结论：单侧原发性BPPV患者双侧前庭耳石器传导通路功能受损状况，可以通过oVEMP和cVEMP检测进行客观评估，并且oVEMP的异常率比cVEMP高。

Primary benign paroxysmal positional vertigo vestibular detection of evoked myogenic potential significance

To analyze the clinical significance of ocular vestibular evoked myogenic potentials （oVEMP） and cervical vestibular evoked myogenic potentials （cVEMP） in primary unilateral benign paroxysmal positional vertigo （BPPV）. Method：Fifty-two patients with unilateral primary BPPV （BPPV group） and 38 nor- mal subjects （control group） received ocular vestibular evoked myogenic potential （oVEMP） and cervical vestibu- lar evoked myogenic potential （cVEMP） test using tone burst stimuli. The response rate, latency and amplitude were analyzed. Result： In BPPV group, the response rate of oVEMP was 46.15 % in lesioned side and 48.08 %in healthy side, respectively. The response rate of cVEMP was 67.31 % in lesioned side and 65.38 %in healthy side, respectively. In control group, the response rate on the left ear was 84.21% for oVEMP and 92.11% for cVEMP. On the right ear, was 81.58% for oVEMP and 94.74% for cVEMP in control group, there was no sig- nificant difference in cVEMP and oVEMP P1, N1 N1-P1 latency and amplitude between left and right ear. The in- teraural amplitude ratio and asymmetry of cVEMP and oVEMP was significantly different between BPPV group and control group （P〈0.05）. Conclusion： Unilateral primary BPPV with bilateral impaired vestibular otolith path- ways function can be objectively evaluated by oVEMP and cVEMP detection. Abnormal oVEMP responses were more frequently detected than cVEMP.