| GJB2相关非综合征性感音神经性聋人工耳蜗植入后的疗效观察 |
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| 引用本文： | 蔡超婵,黄莎莎,高雪,黄邦清,袁永一,王国建,康东洋,韩东一,戴朴. GJB2相关非综合征性感音神经性聋人工耳蜗植入后的疗效观察[J]. 临床耳鼻咽喉头颈外科杂志, 2014, 0(13): 972-974 |
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| 作者姓名： | 蔡超婵 黄莎莎 高雪 黄邦清 袁永一 王国建 康东洋 韩东一 戴朴 |
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| 作者单位： | 解放军总医院耳鼻咽喉头颈外科北京,1008530 |
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| 摘 要： | 目的：评价携带GJB2基因突变的儿童人工耳蜗植入后的疗效。方法：对40例携带GJB2基因突变的人工耳蜗植入患儿进行疗效评估，测试内容包括：声场助听听阈测试、（婴幼儿）有意义听觉整合量表、听觉行为分级标准评分、言语可懂度分级标准评分及普通话早期言语感知测试。以80例未检出已知热点突变者为对照组。结果：携带GJB2基因突变的患儿术后声场助听听阈优于对照组，其余测试与对照组比较差异无统计学意义（P〉0．05）。结论：携带GJB2基因突变的非综合征性感音神经性聋患儿适于行人工耳蜗植人手术，术后效果满意。
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| 关 键 词： | GJB2基因 人工耳蜗植入 |
Assessment of the curative effective of cochlear implantation in childer with GJB2-associated NSSNHL |
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| CAI Chaochan,HUANG Shasha,GAO Xue,HUANG Bangqing,YUAN gongyi,WANG Guojian,KANG Dongyang,HAN Dongyi,DAI Pu. Assessment of the curative effective of cochlear implantation in childer with GJB2-associated NSSNHL[J]. Journal of clinical otorhinolaryngology, head, and neck surgery, 2014, 0(13): 972-974 |
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| Authors: | CAI Chaochan HUANG Shasha GAO Xue HUANG Bangqing YUAN gongyi WANG Guojian KANG Dongyang HAN Dongyi DAI Pu |
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| Affiliation: | (Department of Otolaryngology-Head and Neck Surgery, Chinese PLA General Hospital, Bei jing, 100853, China) |
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| Abstract: | Objective：To analyze the curative effect of CI in children with GJB2-associated NSSNHL.Method：The evaluations of curative effect with CI include auditory threshold,IT-MAIS/MAIS,CAP,SIR,MESP.The outcomes of 40cases with GJB2-associated NSSNHL were compared 80patients with negative results of screening of gene mutation（control group）.Result：In comparison with control group,the auditory threshold in children with GJB2-associated NSSNH is better,however had no significant difference in other tests（P〉0.05）.Conclusion：CI could be performed on children with GJB2-associated NSSNHL.Postoperative outcomes of hearing and speech were satisfied. |
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| Keywords: | GJB2gene cochlear implantation |
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