| Parallel decline of CD8＋CD38＋ lymphocytes and viremia in treated hepatitis B patients |
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| 作者姓名： | Cao W Qiu ZF Li TS |
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| 作者单位： | Department of Infectious Diseases, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China |
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| 基金项目： | Supported by National Key Technologies R&D Program for the 11th Five-year Plan,No. 2008ZX10001-006 |
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| 摘 要： |
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| 收稿时间： | 2010 Aug 20 |
Parallel decline of CD8+CD38+ lymphocytes and viremia in treated hepatitis B patients |
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| Cao W,Qiu ZF,Li TS.Parallel decline of CD8+CD38+ lymphocytes and viremia in treated hepatitis B patients[J].World Journal of Gastroenterology,2011,17(17):2191-2198. |
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| Authors: | Cao Wei Qiu Zhi-Feng Li Tai-Sheng |
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| Institution: | Wei Cao,Zhi-Feng Qiu,Tai-Sheng Li,Department of Infectious Diseases,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing 100730,China |
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| Abstract: | AIM:To assess the peripheral T lymphocyte subsets in chronic hepatitis B virus(HBV) infection,and their dynamics in response to adefovir dipivoxil monotherapy.METHODS:Proportions and absolute counts of peripheral natural killer cells,B cells,CD8+,CD4+,CD8+ CD38+,CD8+CD28+ and CD4+CD28+ T cells were determined using three-color flow cytometry in chronic hepatitis B patients(n = 35),HBV carriers(n = 25) and healthy controls(n = 35).Adefovir dipivoxil was initiated in 17 chronic hepatitis B patients who were r... |
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| Keywords: | Hepatitis B virus Chronic hepatitis B CD8 CD38 T cell subsets |
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