Hepatitis B virus and hepatocellular carcinoma at the miRNA level |
| |
| Authors: | Zhang Zhen-Zhen Liu Xiang Wang De-Qiang Teng Mai-Kun Niu Li-Wen Huang Ai-Long Liang Zhi |
| |
| Affiliation: | Key Laboratory of Molecular Biology on Infectious Diseases, Ministry of Education, Institute for Viral Hepatitis, the Second Affiliated Hospital and Children's Hospital of Chongqing Medical University, Chongqing 400016, China. |
| |
| Abstract: | AIM: To study Hepatitis B virus (HBV) infection and its association with hepatocellular carcinoma (HCC) at the miRNA level.METHODS: Three cellular models were used to investigate miRNA expression changes during HBV infection: human HepG2 hepatoblastoma cell line as a model without HBV infection;HepG2 cell line transfected with a 1.3-fold full-length HBV genome as an acute infection model;and HepG2.2.15 cell line,which is derived from HepG2 and stably transfected with a complete HBV genome,as a chronic infec... |
| |
| Keywords: | Hepatitis B virus Hepatocellular carcinoma MiRNA |
| 本文献已被 CNKI 维普 PubMed 等数据库收录！ |
