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Association between ITGA2 C807T polymorphism and gastric cancer risk |
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| Authors: | Chen Jie Liu Nan-Nan Li Jia-Qi Yang Li Zeng Ying Zhao Xiao-Mei Xu Lin-Lin Luo Xuan Wang Bin Wang Xue-Rong |
| Affiliation: | Jie Chen,Nan-Nan Liu,Jia-Qi Li,Ying Zeng,Xiao-Mei Zhao,Lin-Lin Xu,Xuan Luo,Bin Wang,Xue-Rong Wang,Department of Pharmacology,Nanjing Medical University,Nanjing 210029,Jiangsu Province,China Li Yang,Department of General Surgery,First Affiliated Hospital of Nanjing Medical University,China |
| Abstract: | AIM:To evaluate the impact of the ITGA2 gene polymorphism on gastric cancer risk.METHODS:A hospital-based case-control study was conducted,including 307 gastric cancer patients and 307 ageand gender-matched control subjects.The genotypes were identified by polymerase chain reaction-restriction fragment length polymorphism assay.RESULTS:The frequencies of the wild and variant genotypes in cases were significantly different from those of controls (P=0.019).Compared with individuals with the wild genotype CC,s... |
| Keywords: | Gastric cancer Integrin ITGA2 Polymorphism Genotype |
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