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IL28B polymorphisms associated with therapy response in Chilean chronic hepatitis C patients |
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| Authors: | Venegas Mauricio Villanueva Rodrigo A González Katherine Brahm Javier |
| Affiliation: | Mauricio Venegas,Rodrigo A Villanueva,Katherine González,Javier BrahmMauricio Venegas,Javier Brahm,Centro de Estudios Avanzados de las Hepatitis Virales,Sección de Gastroenterología,Departamento de Medicina,Hospital Clínico Universidad de Chile,8340457 Santiago,Chile Rodrigo A Villanueva,Laboratorio de Virus Hepatitis,Programa de Virología,Instituto de Ciencias Biomédicas,Facultad de Medicina,Universidad de Chile,Chile |
| Abstract: | AIM:To analyze the association of three IL28B single nucleotide polymorphisms with response to therapy in Chilean patients infected with hepatitis C virus CV.METHODS:We studied two groups of patients with chronic CV infection genotype 1,under standard combined treatment with pegylated interferon plus ribavirin.One group consisted of 50 patients with sustained virological response,whereas the second group consisted of 49 null responders.In order to analyze the IL28B single nucleotide polymorphisms rs12979860... |
| Keywords: | IL28B Hepatitis C virus Chile Pegylated interferon Ribavirin |
| 本文献已被 CNKI PubMed 等数据库收录！ | |