Optimized management of advanced hepatocellular carcinoma: four long-lasting responses to sorafenib |
| |
| Authors: | Abbadessa Giovanni Rimassa Lorenza Pressiani Tiziana Carrillo-Infante Cynthia Cucchi Emanuele Santoro Armando |
| |
| Institution: | Giovanni Abbadessa,Lorenza Rimassa,Tiziana Pressiani,Armando Santoro,Department of Medical Oncology and Hematology,Istituto Clinico Humanitas,20089 Rozzano,Milan,Italy Giovanni Abbadessa,Department of Human Pathology and Oncology,Program of Genetic Oncology,University of Siena,53100 Siena,Italy Cynthia Carrillo-Infante,Program of Molecular Pathology,Italy Emanuele Cucchi,Department of Radiology and Ultrasound,Polidiagnostico CAM,2005... |
| |
| Abstract: | The therapeutic options for hepatocellular carcinoma (HCC) have been so far rather inadequate.Sorafenib has shown an overall survival benefit and has become the new standard of care for advanced HCC.Nevertheless,in clinical practice,some patients are discontinuing this drug because of side effects,and misinterpretation of radiographic response may contribute to this.We highlight the importance of prolonged sorafenib ad-ministration,even at reduced dose,and of qualitative and careful radiographic evaluation.... |
| |
| Keywords: | Hepatocellular carcinoma Sorafenib Drug toxicity Response criteria Decision making |
| 本文献已被 CNKI PubMed 等数据库收录！ |
|
