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Marchiafava-Bignami disease: serial changes in corpus callosum on MRI
Authors:K. H. Chang  S. H. Cha  M. H. Han  S. H. Park  D. L. Nah  J. H. Hong
Affiliation:(1) Department of Radiology, Seoul National University College of Medicine, Seoul, Korea;(2) Department of Neurology, Youngdeungpo City Hospital, Seoul, Korea;(3) Department of Radiology, Sungae Hospital, Seoul, Korea;(4) Department of Diagnostic Radiology, Seoul National University Hospital, 28 Yongon-dong, Chongno-gu, 110-744 Seoul, Korea
Abstract:Summary Serial MRI findings of changes in corpus callosum lesions in two cases of Marchiafava-Bignami disease are presented. In both, MRI displayed diffuse swelling of the corpus callosum in the acute stage, thought to represent oedema and demyelination. In the chronic stage, in addition to atrophy of the corpus callosum with presumed focal necrosis, previously undescribed focal hypointensity on T2-weighted images, of unknown cause, was observed in the corpus callosum.This work was supported by a grant from the Korea Radiologic Research Fund (1992)
Keywords:Degenerative disease  Magnetic resonance imaging  Corpus callosum  Marchiafava-Bignami disease
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