| 益生菌在过敏性疾病中的应用及作用机制 |
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| 引用本文： | 王瑰娜.益生菌在过敏性疾病中的应用及作用机制[J].国际儿科学杂志,2012,39(1). |
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| 作者姓名： | 王瑰娜 |
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| 作者单位： | 中国医科大学附属盛京医院儿科, 沈阳,110004 |
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| 摘 要： | 益生菌通过促进树突状细胞释放细胞因子,改变Th1/Th2平衡,使免疫反应向Th1细胞方向进行,抑制Th2细胞反应,从而增强宿主的免疫功能.研究表明益生菌在特异性皮炎、哮喘及过敏性鼻炎等IgE相关过敏性疾病的预防和治疗中发挥一定的作用,但由于过敏性疾病的病因复杂、诱因众多,目前益生菌对其作用尚无一致的结论,需进一步进行循证医学研究.
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| 关 键 词： | 益生菌 IgE T细胞 树突状细胞 过敏性疾病 |
The application and mechanisms of probiotics in allergic diseases |
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| WANG Gui-na.The application and mechanisms of probiotics in allergic diseases[J].International Journal of Pediatrics,2012,39(1). |
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| Authors: | WANG Gui-na |
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| Abstract: | Probiotics stimulate dendritic cells exert regulatory functions by promoting the release of cytokines,which change the balance of Th1/Th2.This process mediates Th1 cell response instead of Th2 to enhance immune function.Probiotics have shown preventive and therapeutic potential for diseases,including several IgE-related diseases,such as atopic dermattis,asthma and allergic rhinitis.However,because of complex causes and numerous incentives,there is no consistent conclusion regarding probiotics application in allergic diseases.Further evidence-based medical researches will be required in the future. |
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| Keywords: | Probiotics IgE T cell Dendritic cell Allergic diseases |
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