| 宫颈癌治疗性疫苗临床研究进展 |
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| 引用本文： | 黄云霞. 宫颈癌治疗性疫苗临床研究进展[J]. 国际生物制品学杂志, 2012, 35(1). DOI: 10.3760/cma.j.issn.1673-4211.2012.01.006 |
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| 作者姓名： | 黄云霞 |
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| 作者单位： | 200052,上海生物制品研究所有限责任公司第二研究室 |
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| 摘 要： | 宫颈癌的发生与高危型人乳头瘤病毒( human papillomavirus,HPV)的持续感染有关.随着对HPV及其致病机制的深入研究,已经开发了多种用于宫颈癌生物免疫治疗的疫苗,有些已进入临床试验.此文对已进入临床试验阶段的宫颈癌疫苗的设计策略和临床试验进展做一综述.
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| 关 键 词： | 人乳头瘤病毒 宫颈肿瘤 治疗性疫苗 临床试验 |
Clinical research advance in therapeutic vaccines against cervical cancer |
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| HUANG Yun-xia. Clinical research advance in therapeutic vaccines against cervical cancer[J]. International Journal of Biologicals, 2012, 35(1). DOI: 10.3760/cma.j.issn.1673-4211.2012.01.006 |
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| Authors: | HUANG Yun-xia |
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| Abstract: | Persistent infection by high-risk human papillomavirus (HPV) has been found associated with most cervical cancers.With the further study on HPV and its pathogenic mechanism,several therapeutic vaccines against cervical cancer have been developed,and even in clinical trial phrase.In this paper,the progress in clinical trials and design strategies of therapeutic HPV vaccines are reviewed. |
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| Keywords: | Human papillomavirus Uterine cervical neoplasms Therapeutic vaccines Clinical trials |
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