| 内质网应激中ATF-6调控细胞凋亡及相关疾病 |
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| 引用本文： | 张一冰,徐盟,关雅迪,石玉秀.内质网应激中ATF-6调控细胞凋亡及相关疾病[J].中外医疗,2012,31(30):182-183. |
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| 作者姓名： | 张一冰 徐盟 关雅迪 石玉秀 |
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| 作者单位： | 1. 中国医科大学,辽宁沈阳,110001
2. 中国医科大学组织学与胚胎学教研室,辽宁沈阳,110001 |
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| 摘 要： | 许多异常反应都会引起内质网应激,进而激活未折叠蛋白反应。当未折叠反应仍不能缓解内质网蛋白负荷时,就会通过多条途径引起细胞凋亡,并引起相关疾病,如糖尿病,躁郁症,神经退行性疾病和创伤后应激反应PTSD等。该文主要论述活化转录因子6在ER应激中调控细胞凋亡的机制以及引起的相关疾病。
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| 关 键 词： | 内质网应激 未折叠蛋白反应 ATF-6细胞 |
Endoplasmic Reticulum Stress in ATF-6 Regulation of Apoptosis and Its Related Diseases |
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| ZHANG Yibing
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XU Meng
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GUAN Yadi
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SHI Yuxiu.Endoplasmic Reticulum Stress in ATF-6 Regulation of Apoptosis and Its Related Diseases[J].China Foreign Medical Treatment,2012,31(30):182-183. |
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| Authors: | ZHANG Yibing XU Meng GUAN Yadi SHI Yuxiu |
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| Institution: | 1.China Medical University Clinical Medicine System for Seven Years Shenyang 110001,China;2.China Medical University Department of histology and embryology,Shenyang 110001,China |
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| Abstract: | |
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| Keywords: | Endoplasmic Reticulum Stress The Unfolded Protein Response ATF-6 Cell Apoptosis Related Diseases |
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