The usefulness of pelvic lymphadenectomy in bladder cancer |
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| Authors: | Monzó J I Herranz Amo F Cabello Benavente R Hernández Fernández C |
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| Affiliation: | 1. Department of Internal Medicine and Therapeutics, University of Pavia and Fondazione IRCCS Policlinico S. Matteo, Pavia, Pavia, Italy;2. Center for the Study of Endocrine-Metabolic Pathophysiology and Clinical Research, University of Pavia, Pavia, Italy;3. Molecular Medicine Laboratory, University of Pavia, Pavia, Italy;4. Unit of Nephrology, Dialysis and Transplantation, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy;5. Biometric Unit, Fondazione IRCCS Policlinico S. Matteo, Pavia, Italy;6. PhD School in Experimental Medicine, University of Pavia, Pavia, Italy |
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| Abstract: | ObjetiveTo assess the usefulness of pelvic lymphadenectomy in bladder cancer.Methods and ResultsWith the followings key words: “bladder cancer, lymphadenectomy, lymph node metastasis” we search in Medline/PubMed database for papers published during the last ten years. Thirty three papers fulfilling the search criteria were selected.ConclusionsIt does not exist any randomized prospective study comparing different pelvic lymphadenectomy techniques. Nodal metastasis in bladder cancer after radical cystectomy and pelvic lymphadenectomy ranged between 18% and 28%. Standard lymphadenectomy could improve tumor staging and probably survival in selected patients. It is advisable to remove, as a quality parameter, at least 10 to 14 nodes in a pelvic lymphadenectomy. Lymph node density seems to predict survival better than TNM staging system. It is advisable to perform separate lymph node dissection rather than en-bloc. |
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