慢性肾脏病情感障碍及危险因素研究

目的：了解慢性。肾脏病患者焦虑和抑郁的发生情况及其危险因素。方法：采用横断面调查，对住院病人进行SAS和SDS量表测评。结果：慢性。肾脏病患者焦虑和抑郁的发生率分别为53、4％、60．9％，其中。肾功能不全组又明显高于。肾功能正常组，焦虑的发生率分别为72．9％、23．9％；抑郁的发生率分别为74．3％、39．5％。尿毒症患者不同的替代治疗方式对焦虑的发生和抑郁严重程度的分布有影响，。肾移植病人焦虑的发生率最低。多因素分析表明Cer降低(OR=0．911，0．831-0．999)、自费(OR=3．528，95％CI：1．242-10．018)和家庭低收入(OR=3．493，95％CI：1．252-9．747)是抑郁的危险因素；Ccr降低(OR=0．973，0．959-0．981)和家庭低收入是焦虑的危险因素(OR=2．571，95％CI：1．108-5．969)。结论：慢性。肾脏病患者，特别是。肾功能不全患者，焦虑和抑郁的发生率高于普通人群；Ccr降低是焦虑和抑郁的危险因素。医药费来源于属于自费和低家庭收入是抑郁发生的危险因素；低家庭收入是焦虑发生的危险因素。

The Study of Affective Disorder and Risk Factor in Chronic Renal Disease

Objective:To investigate the prevalence of anxiety and depression in patients with chronic renal disease and their risk factors.Method:It is a cross-section survey.Self-Rating Anxiety Scale(SAS)and Self-Rating Depression Scale(SDS)were administered to hospitalized patients.Result:The prevalence of anxiety an depression in patients with chronic renal disease were 54.3% and 60.9%,respectively.Patients with chronic renal failure suffered more anxiety an depression than patients without renal failure,the prevalence were 72.9% vs.23.9% and 74.3% vs.39.5%,respectively.The prevalence of anxiety and severity of depression were different according to different replacement treatments in uremia.Kidney transplant recipients suffered less anxiety.That the way of payment of medical expenditure is at one's own expenses(OR=3.528,95%CI:1.242-10.018),and decreased Ccr(OR=0.911,0.831-0.999)or low income family(OR=3.493,95%CI:1.252-9.474)were the risk factors for depression;decreased Ccr(OR=0.973,0.959-0.981)and low income family(OR=2.571,95%CI:1.108-5.969)were the risk factors for anxiety.Conclusion:The prevalence of anxiety and depression were significantly higher in patients with chronic renal disease and chronic renal failure those normal people.Ccr,family income and way of payment of the medical expenditure were inversely associated with affective disorders.