Value of contrast-enhanced ultrasonography for detecting renal infarcts proven by contrast enhanced CT. A feasibility study |
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Authors: | Michele Bertolotto Alberto Martegani Luca Aiani Roberta Zappetti Stefano Cernic Maria Assunta Cova |
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Institution: | (1) UCO di Radiologia, Università di Trieste, Ospedale di Cattinara, Strada di Fiume 449, 34149 Trieste, Italy;(2) Servizio di Diagnostica per Immagini, Ospedale Valduce, Via Dante 11, 22100 Como, Italy |
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Abstract: | The effectiveness of contrast-enhanced ultrasonography (CEUS) in the evaluation of patients with acute renal infarcts was
investigated, using contrast-enhanced helical computed tomography (CT) as the reference imaging procedure. Twenty-seven consecutive
patients with acute renal infarcts detected with contrast-enhanced helical CT underwent CEUS. Digital cine-clips of CEUS were
evaluated by two independent readers blinded to CT findings. Image quality was rated subjectively on a four-point scale. Then,
readers were asked to assign a confidence level in diagnosis of renal infarct at the upper pole, medium portion, and lower
pole of each kidney according to a five-degree scale, ranging from definitely absent to definitely present. ROC curve analysis
was employed to assess the overall confidence of diagnosis of infarct, and weighted kappa values were calculated to assess
inter-reader agreement. The subjective image quality of CEUS was lower than the image quality of CT at the upper poles. However,
the diagnostic performance of CEUS was excellent (area under receiver-operator characteristic curve 0.992 ± 0.006 for reader
1; 0.991 ± 0.007 for reader 2), with very good inter-reader agreement (weighted kappa value = 0.83). CEUS is a reproducible
tool to detect acute renal infarcts in men, with a diagnostic performance approaching that of CT.
This study was presented as a scientific paper for ECR 2007 (control number: 3596) |
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Keywords: | Microbubble contrast agents Ultrasound Kidney Renal infarction Contrast-enhanced ultrasonography |
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