狭叶崖爬藤化学成分的研究

目的 研究我国特有药用植物狭叶崖爬藤Tetrastigma hypoglaucum的化学成分，为阐明其有效成分提供依据。方法 利用各种色谱技术进行分离，根据化合物的光谱数据（IR，MS，^1HNMR,^13CNMR)和化学方法鉴定其结构。结果 从狭叶崖爬藤地上部分分离并鉴定了10个化合物，分别为β-谷甾醇（β-sitosterol,I)，棕榈酸（palmitic acid,Ⅱ），正二十五烷（pentacosane,Ⅲ），胡萝卜苷（daucosterol,Ⅳ），白藜芦醇（resveratrol,Ⅴ），没食子酸（gallic acid,Ⅵ），没食子酸乙酯（ethyl gallate,Ⅶ），儿茶素（catechin,Ⅷ），7-氧-没食子酰基-儿茶素（7-O-galloylcate-chin,IX）和3，3′-二甲氧基鞣花酸-4-氧-葡萄糖苷（3，3′-dimethoxy ellagic acid-4-O-β-D-glucopyranoside,X)。结论 所有化合物均系首次从该植物中分离得到。

Studies on chemical constituents from Tetrastigma hypoglaucum

Object To investigate the chemical constituents in the aerial part of Tetrastigma hypoglau-cum Planch. native to China in order to obtain a more comprehensive understanding of its effective compo-nents. Methods Compounds were isolated by various column chromatographies with silica gel. Theirstructures were elucidated by spectral analysis (IR, MS, 1HNMR, 13CNMR) and chemical evidence. Re-sults Ten compounds were isolated from the ethanol extracts of T. hypoglaucum, which were identifiedas β-sitosterol (Ⅰ), palmitic acid (Ⅱ), pentacosane (Ⅲ), daucosterol (Ⅳ), resveratrol (Ⅴ), gallic acid(Ⅵ), ethyl gallate (Ⅶ), catechin (Ⅷ), 7-O-galloylcatechin (Ⅸ), and 3, 3'-dimethoxy ellagic acid-4-O-β-D-glucopyranoside (Ⅹ). Conclusion All compounds were obtained from this plant for the first time.