C1: molecular interactions with activating systems. |
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Authors: | R B Sim K B Reid |
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Affiliation: | Dept of Biochemistry, University of Oxford, UK. |
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Abstract: | The molecular events controlling complement activation have been gradually unravelled over the past three decades, stimulated by improved isolation procedures and a better understanding of the roles of individual proteins. In this review, Bob Sim and Ken Reid examine the interactions between C1q and its numerous ligands in the initiation of the classical pathway cascade. |
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