Seroepidemiology of human group C rotavirus in South Africa |
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Authors: | Steele A D James V L |
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Affiliation: | MRC/Medunsa Diarrhoeal Pathogens Research Unit, Medical University of Southern Africa, Pretoria, South Africa. adsteele@medunsa.ac.za |
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Abstract: | Sera from three separate healthy population cohorts were used to determine the incidence of group C rotavirus infections in 1,356 South Africans. Using an enzyme-linked immunosorbent assay based on a recombinant group C rotavirus VP6 protein, the total percent positivity was found to be 34.4% (range, 33 to 38%), with almost half of the population infected after the age of 20 years. |
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