Renal cell carcinoma in a child presented as bilateral femur neck fractures caused by severe vitamin D deficiency |
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Authors: | Aviner Shraga Dabby Dan London Daniel Feinmesser Meora Ash Shifra Steinberg Ran Jakim Itzhak |
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Affiliation: | Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Isreal. aviners@barzi.health.gov.il |
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Abstract: | An Ethiopian girl 14 years and 11 months of age presented with bilateral transcervical hip fractures. Workup revealed severe vitamins D and C deficiencies with secondary hyperparathyroidism. Imaging studies showed bilateral radiolucent metaphyseal bands with multiple lytic lesions in long bones. A mass in the right flank was found to be renal cell carcinoma (RCC). Currently, 9 months postsurgery and supplemental therapy, the patient is fully ambulatory and free of pain. This first report of asymptomatic RCC in severely vitamin D deficient child highlights the relation of RCC to vitamin D deficiency and emphasizes the importance of careful evaluation of these children. |
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