Arthrites réactionnelles secondaires à la BCG-thérapie. Deux observations et revue de la littérature |
| |
Authors: | S Miranda M Vernet F Héron O Vittecoq H Levesque I Marie |
| |
Institution: | 1. Département de Médecine interne, CHU de Rouen-Boisguillaume, 1, rue de Germont, 76031 Rouen cedex, France;2. Service de rhumatologie, CHU de Rouen-Boisguillaume, 76031 Rouen cedex, France |
| |
Abstract: | IntroductionIntravesical bacillus Calmette-Guérin (BCG) therapy-associated articular complications are uncommon, occurring in only 0.5 to 1% of the patients.ObservationsWe report two patients who were given intravesical BCG therapy for superficial bladder cancer. Both patients developed polyarthritis and fever related to intravesical BCG instillation. The outcome of articular manifestations was favorable after administration of nonsteroidal anti-inflammatory therapy.ConclusionIntravesical BCG therapy-associated articular complications should not be overlooked, as they may result in high morbidity. Nevertheless, the diagnosis of intravesical BCG therapy-related reactive arthritis should be discussed after excluding infectious arthritis due to Mycobacterium bovis. Therefore, joint fluid microbiological tests (cultures, PCR) are required in the patients receiving intravesical BCG who develop arthritis. |
| |
Keywords: | Tumeur vé sicale BCG-thé rapie Effets secondaires Manifestations articulaires Arthrite ré actionnelle |
本文献已被 ScienceDirect 等数据库收录! |
|