Effects of posttrial vasopressin injections on appetitively motivated learning in rats |
| |
Authors: | Josette Alliot Tatiana Alexinsky |
| |
Affiliation: | Laboratoire de Psychophysiologie, Université Clermont II B.P. 45, 63170 Aubiere, France;Département de Psychophysiologie, LPN-CNRS, Gif-sur-Yvette 91190 Gif-Sur-Yvette, France |
| |
Abstract: | Sixty male rats, maintained on 23-hr food deprivation were trained on two types of appetitive tasks: bar press responding under a CRF schedule, and under a differentially reinforced (light+, dark?) schedule. Performance of rats treated with lysine vasopressin, injected immediately after each training session, was compared to that of control animals injected with saline. In the CRF stage, treated animals reached learning criterion significantly later than did control rats, and made significantly fewer bar presses. During acquisition and extinction of a light-dark discrimination, learning and retention were not altered by vasopressin, though the number of bar presses was significantly decreased, and a differential effect was found according to previous CRF performance. The results are discussed considering the hypothesis of a facilitatory effect of vasopressin on memory processes. |
| |
Keywords: | Vasopressin Memory CRF Discrimination learning Appetitive task |
本文献已被 ScienceDirect 等数据库收录! |
|