莫昔沙星治疗早发医院获得性肺炎34例

［摘要］目的观察莫昔沙星治疗组34例，治疗早发医院获得性肺炎的临床疗效。方法早发医院获得性肺炎患者67例随机分为两组，治疗组34例，予盐酸莫昔沙星氯化钠注射液100 mL(含莫昔沙星400 mg)静脉滴注，qd,连用7 d，对照组33例，予头孢曲松钠针剂2.0 g加入0.9%氯化钠注射液静脉滴注，qd，连用7 d。观察临床指标，细菌学，临床疗效及安全性。结果治疗组和对照组的临床有效率分别为91.2%和63.6%，两组比较差异有显著性，（P＜0.05＝。结论莫昔沙星针剂治疗早发医院获得性肺炎疗效显著，可用于早发性医院获得性肺炎的治疗。

Observation of the Curative Effect of Moxifloxacin on 34 Cases of Early Hospital Acquired Pneumonia

Objective To study the curative effect of moxifloxacin in the treament of early hospital acquired pneumonia. Methods Sixty seven cases of early hospital acquired pneumonia were randomly divided into moxifloxacin(400 mg i.v.drip qd for 7 d) treament group(34 cases) and ceftrlaxone(ampule 2.0 g,i.v.drip qd for 7 d) treament group(33 cases).The therapeutic effect and safty were compared between the two groups. Results The effective rate in moxifloxacin treament group was 91.2% and 63.6% in ceftrlaxone treament group.The effective rate in moxifloxacin treament group was significantly higher than that in ceftrlaxone treament group(P<0.05). Conclusion Moxifloxacin is a safe and effective antibiotic for the treament of early hospital acquired pneumonia.