锁阳属植物的化学成分及药理作用(英文)

锁阳是锁阳科植物Cynomorium songaricum的根茎,是以具有强壮作用而著名的中药材。生长在北非及地中海地区的同属植物C.coccineum被阿拉伯人看作是"宝药"。研究表明锁阳属植物的主要成分为酚类、甾体和三萜类化合物等。锁阳属植物的药理作用包括抗氧化、提高免疫力、抗糖尿病及神经保护等。锁阳的一些化学成分结构容易发生变化,因此不同生产条件得到的锁阳类药物成分会有所不同。该文综述锁阳属植物的药理作用及化学成分,检索的文献截至2011年底。

Chemical constituents and pharmacologic actions of Cynomorium plants

The stem of Cynomorium songaricum is a traditional Chinese medicine reputed to have tonic effects. C. coccineum growing in northern Africa and the Mediterranean region is regarded in Arabian medical practice as the ＂treasure of drugs＂. The major constituents of Cynomorium plants have been revealed to be phenolic compounds, steroids, triterpenes, etc. Pharmacologic studies showed that the Cynomorium plants had antioxidant, immunity-improving, anti-diabetic, neuroprotective, and other bioactivities. Some chemical constituents in Cynomorium plants are unstable, implying that the chemical components of the herbal medicines produced under different conditions may be variable. This review covers the literature published until December, 2011 and describes the pharmacologic effects and secondary metabolites of Cynomorium species.