吴兴县二年痢疾杆菌菌型分布及耐药性的调查

本文报告吴兴县1978~1979年109株痢疾杆菌中优势菌二年均为福氏菌群,占81.6%;次为宋内氏菌,占13.8%。未发现志贺氏Ⅰ型菌,并首次分离得鲍氏菌。在福氏菌群中,以1a型比例最高,达64%;其次为2a型,占18%。
十三种抗菌药物敏感试验反映出痢疾杆菌对常用抗菌药物都有不同程度的耐药性,尤对常用药物氯霉素、合霉素、四环素、土霉素,敏感株仅占28.7%、22.8%、20.8%、18.8%、敏感药物当推选痢特灵、庆大霉素、新霉素和卡那霉素。文内介绍了在纸片药物敏感试验培养基中加入1%葡萄糖和指示剂的改良药敏试验方法,有易于观察抑菌结果的优点。

Two-year-investigation on Geographical Distribution of Serotypes and Drug Resistance in Shigella at Wuxing County

109 strains of the bacillus of dysentry were isolated during 1978 to 1979 in Wu Xing County. The predominant strain was S flexneri (81.6%), and then S sonnei (13.8%), whereas S. dysenteriae type 1 was not found. S. boydii was isolated for the first time in this district. TyPe Ia of S. flexneri seemed to have the highest percentage among S. flexneri strains (64%) and the next(18%) type IIa.
13 kinds of drugs were tested in vitro for sensitivity. It was found that 28.7%,22.8%,20.8%and 18.8% of the strains were sensitive to chloramphenicol syntomycin, tetracycline and terramycin respectively. The bacteria were more sensitive to furazolidone, gentamycin, neomycin and kanamycin.
It was recommended that 1% glucose and a kind of indicator added into the culture medium could improve the "slice drug seneitivity test",because it facilitated the observation of the result of bacteria inhibition.