The effects of acetylcholine on bulbar respiratory related neurones |
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| Authors: | M. P. Morin-Surun J. Champagnat M. Denavit-Saubie S. Moyanova |
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| Affiliation: | (1) Laboratoire de Physiologie Nerveuse, Département de Neurophysiologie Appliquée, C.N.R.S., F-91190 Gif-sur-Yvette, France;(2) Present address: Institute of Physiology, Bulgarian Academy of Sciences, Bontcher Street, BG-1113 Sofia, Bulgaria |
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| Abstract: | Summary The effects of cholinergic agonists and antagonists applied by microiontophoresis to bulbar respiratory neurones were determined in different preparations: cats anaesthetized by pentobarbital and immobilized by gallamine triethiodide, intercollicular decerebrate cats either not immobilized or immobilized by gallamine triethiodide. Respiratory neurones located at the bulbar level exhibited a muscarinic cholinergic sensitivity in all preparations. Muscarinic responses were either excitatory or inhibitory. The number of neurones showing excitatory responses was lower under pentobarbital anaesthesia than in decerebrate cats. |
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| Keywords: | Cholinergic agents Anticholinergic agents Pentobarbital Respiratory neurones |
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