| 血清CEA、CA199、CA724联合黏膜端粒酶检测对大肠癌诊断及预后评价的价值 |
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| 引用本文： | 毕超,肖创情,黄修海,张一帆,刘祥.血清CEA、CA199、CA724联合黏膜端粒酶检测对大肠癌诊断及预后评价的价值[J].医学临床研究,2008,25(8). |
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| 作者姓名： | 毕超 肖创情 黄修海 张一帆 刘祥 |
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| 作者单位： | 解放军第163医院,湖南,长沙,410003 |
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| 摘 要： | 目的]探讨血清CEA、CA199、CA724和黏膜端粒酶单项或多项联栓对大肠癌的诊断及预后评价意义.方法]用电化学发光法检测82例大肠癌患者和42例良性病变及38例健康人血清中的CEA、CA199、CA724和黏膜端粒酶含量并分析敏感性、特异性.结果]大肠癌血清CEA、CA199、CA724和黏膜端粒酶含量显著高于正常健康对照组及良性病变组(P<0.05),联合检测其敏感性和特异性明显高于单项检测(P<0.05).Dukes分期超高,血清CEA、CA199、CA724和黏膜端粒酶的阳性率依次增高,CA724和黏膜端粒酶和病理分型相关,分化程度越低,阳性率越高.结论]血清CEA、CA199、CA724和黏膜端粒酶可用于大肠癌的早期诊断、病情判断,联合检测更具临床意义.
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| 关 键 词： | 结肠直肠肿瘤/血液 癌胚抗原/血液 抗原 肿瘤相关 碳水化合物/血液 端粒 末端转移酶/血液 预后 |
Study on the Clinical Application of Combined Measurement of Serum CEA,CA199,CA724 and Mucosal Telomerase for the Diagnosis and Prognostic Evaluation with Carcinoma of Large Intestine |
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| BI Chao,XIAO Chuang-Jing,HUANG Xiu-Hai,et al.Study on the Clinical Application of Combined Measurement of Serum CEA,CA199,CA724 and Mucosal Telomerase for the Diagnosis and Prognostic Evaluation with Carcinoma of Large Intestine[J].Journal of Clinical Research,2008,25(8). |
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| Authors: | BI Chao XIAO Chuang-Jing HUANG Xiu-Hai |
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| Institution: | BI Chao,XIAO Chuang-Jing,HUANG Xiu-Hai,et al(163 Hospital,liberation army,Changsha 410003,China) |
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| Abstract: | |
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| Keywords: | colorectal neoplasms/BL carcinoembryonic antigen/BL antigens tumor-associated carbohydrate/BL telomerase/BL prognosis |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
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