Production of dysplastic platelets by peripheral blood megakaryoblasts in transient myeloproliferative disorder in Down syndrome |
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| Authors: | Anita Chopra Rajive Kumar Madhulika Kabra |
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| Affiliation: | 1. Laboratory Oncology, Institute Rotary Cancer Hospital (IRCH), New Delhi, India;2. Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India |
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| Abstract: | Monitoring the course of platelet function in HELLP (haemolysis, elevated liver-enzymes and low platelets) syndrome is important for clinical decision-making. We present a primigravid woman developing HELLP syndrome at 29 weeks and 6 days. Platelet function was monitored by multiple electrode aggregometry (MEA), platelet function analyzer (PFA-100®), platelet count and mean platelet volume (MPV) over an 11-day period. MPV and PFA-100® seem better predictors for platelet function than platelet levels. |
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| Keywords: | HELLP syndrome MPV Multiplate® PFA-100® platelets |
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