伽玛刀治疗原发性与继发性癫痫的疗效分析

目的探讨伽玛刀治疗原发性与继发性癫痫疗效。方法回顾性分析我院2002年至2010年接受伽玛刀治疗并且资料完整的155例癫痫病人发作情况,原发性癫痫伽玛刀治疗边缘剂量15～25Gy,继发性癫痫8～20Gy。结果随访时间13～135个月,平均67个月,76例原发性癫痫,有效率68.4%,79例继发性癫痫,有效率79.7%,两者之间无统计学差异,但继发性癫痫满意及显著改善比率较高。结论伽玛刀治疗癫痫安全、有效、且并发症少,继发性癫痫伽玛刀治疗效果可能更好。

Effiicacy of gamma knife for essential and secondary epilepsy

Objective To explore the efficacy of essential and secondary epilepsy underwent gamma knife.Methods To analysis the epilepsy with the clinical data of 155 patients who had seizure,and treated by Leksell-C gamma knife from 2002 to 2010.The marginal dose ranged from 15~25Gy in essential epilepsy and 8~20Gy in secondary epilepsy.Results The follom-up period ranged from 13~135(mean 67)months.The availability of 76 patients with essential epilepsy is 68.4%.The effective rate of 79 patients with secondary epilepsy is 79.7%.The two kind isn’t statistically significant.The percentage of secondary epilepsy after gamma knife with content and predominance improvement is higher.Conclusion Gamma knife is a safe and effective method with low complications to treat epilepsy,which maybe better for secondary epilepsy.