COVID-19 and Obesity: Overlapping of Two Pandemics |
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| Authors: | Maria Alessandra Gammone Nicolantonio D'Orazio |
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| Institution: | Human and Clinical Nutrition Unit, Department of Medical, Oral and Biotechnological Sciences, University G. D''Annunzio, Chieti, Italy |
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| Abstract: | BackgroundThe coronavirus disease 2019 (COVID-19) pandemic has recently led to worldwide research efforts to identify subjects at greater risk of developing more severe illness: overall obesity displayed a strong correlation with critical illness and major severity of COVID-19 manifestations.SummaryObesity and metabolic disorders are closely linked to chronic systemic inflammation. The adipose tissue constitutes a source of cytokines, which configure a low-grade inflammation and a hypercoagulation status; in addition, diagnosis and care of obese patients are often complicated by excess weight and ventilation difficulties.Key MessagesThis review aims to examine the intersection between obesity and adverse outcomes of COVID-19, in order to investigate its preventive and/or therapeutic potential in the management of obesity-related COVID-19 complications. |
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| Keywords: | Obesity COVID-19 Body fat Pandemic Inflammation Thrombosis |
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